The sixth edition of this time-tested text on advanced nursing role development is completely updated to encompass the full complement of current APRN practice roles. Reflecting the evolving spheres of the DNP and CNL, it illuminates in greater depth the transition into practice of APRN master’s and doctoral students and emphasizes the APRN’s all-important role in influencing health policy, global health, and differentiated APRN practice and leadership roles within interprofessional teams. This sixth edition―the only text to address the APRN role globally―continues the conversation on educational requirements and differentiation from certification, and includes expanded coverage of professional issues and research-based practice. Also discussed is the impact of the Patient Protection and Affordable Care Act (and any potential changes) on the current and future APRN role.